The current methods for detecting TB drug resistance are inefficient and imprecise, leading to covering drugs that either cause or exacerbate drug resistance. Chromosomal genetic variation is the primary mechanism through which TB develops resistance to treatment.
A quick diagnosis of multidrug-resistant tuberculosis is now possible due to advances in gene chip detection technology, which can evaluate a patient’s resistance to rifampicin and isoniazid, two of the most important first-line anti-tuberculosis medications.