HLA Typing CapitalBio

HLA Typing Meaning

HLA typing refers to the process of determining the specific alleles present in an individual's human leukocyte antigen (HLA) genes. The HLA system is a group of genes located on chromosome 6 that encode proteins involved in the immune system's recognition and response to foreign substances, such as pathogens or transplanted tissues or organs.

HLA typing is performed through molecular methods, often utilizing techniques like Polymerase Chain Reaction (PCR) and DNA sequencing. These methods analyze specific regions within the HLA genes and identify the alleles present in an individual's genetic makeup.

HLA typing is important for several medical and scientific applications, including organ and tissue transplantation, hematopoietic stem cell transplantation (bone marrow transplantation), predicting disease susceptibility, understanding immune responses, forensic investigations, and population genetics studies.

Matching HLA types between a donor and recipient is crucial in transplantation to minimize the risk of rejection and improve the compatibility of transplanted tissues or organs. In disease research, certain HLA alleles are associated with an increased or decreased risk of developing certain conditions, aiding in understanding genetic factors and designing targeted treatment strategies.

Overall, HLA typing plays a vital role in various fields by providing valuable information about an individual's immune system and genetic compatibility, contributing to personalized medicine and scientific advancements.

HLA Typing Applications

• China Marrow Donor Program

  The largest HLA matching laboratory in cooperation with China Marrow Donor Program, as the contractor of sample bank of the China Marrow Donor Program, nearly 2.43 million samples have been stored.

  
  

• CordBlood Bank

  Has reached a long-term and stable strategic partnership with 5 CordBlood Banks across the country, and is the HLA testing laboratory with the most cooperative cord blood banks in China.

  
  

• Clinical Hospital

  The joint HLA matching laboratory of CapitalBio Technology and Peking University Peoples Hospital was formally signed in August 2015. CapitalBio Technology has a strong alliance with domestic authoritative leukemia diagnosis and treatment hospitals, and will jointly build a top international HLA matching center to benefit patients.

• High Resolution and Accuracy: CapitalBio Technology’s HLA typing service provides high resolution and 100% accuracy. This ensures precise results, which are crucial in medical applications such as organ transplantation, gene therapy, and immunological disease and cancer studies.

• Flexible Testing Sites: The company offers flexibility in testing sites, including HLA class I (A, B, C) and HLA class II (DQB1, DQA1, DPA1, DPB1, DRB1, DRB3, DRB4, DRB5). This flexibility allows for a comprehensive analysis of the HLA system, providing valuable insights for various applications.

• Efficient Sequencing: CapitalBio Technology utilizes capture sequencing, which enables HLA typing in a cost-effective, fast, and high-throughput manner. This efficiency is beneficial in situations where quick results are needed.

• Quality Control and Experience: The company maintains strict quality control measures and has rich practical experience in HLA typing. This ensures reliable results and a high level of service.

• Sample-to-Report Solution: CapitalBio Technology offers a complete sample-to-report solution, simplifying the process for clients and ensuring a seamless experience.

• Wide Application: The HLA typing service provided by CapitalBio Technology has been widely applied in various fields, including organ transplantation, population evolution, gene therapy, as well as immunological disease and cancer studies. This wide application demonstrates the versatility and effectiveness of their HLA typing service.