Folic Acid Utilization Ability Genetic Detection CapitalBio

Name: Folic Acid Utilization Ability Genetic Detection
Brand: CapitalBio Technology Co., Ltd.

Folic acid is mainly involved in nucleic acid, protein synthesis and DNA methylation in the human body, and is an essential micronutrient for the human body. The human body cannot synthesize folic acid on its own and must obtain it from food. But some people develop folic acid deficiencies even when they maintain a normal intake of folic acid.

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Features of Folic Acid Utilization Ability Genetic Detection

Consume The Same Amount Of Folic Acid, Some People Show Folic Acid Deficiency, But Some People Show Excess Folic Acid, Why?

This is mainly because genes determine the ability of each person to metabolize folic acid differently. In the Chinese population, the gene and population ratios related to folic acid metabolism are as follows:

Gene	Loci	Genotype and Proportion in Chinese Population	Gene Function
MTHFR	C677T	CC(Normal, 28.5%), CT(Low risk，49.8%), TT(High risk, 21.7%）	Catalyzes the production of 5-methyltetrahydrofolate, which is involved in methyl transfer and nucleotide synthesis pathways.
MTHFR	A1298C	AA(Normal, 60.3%), AC(Low risk，34.7%), CC(High risk, 5%)
MTRR	A66G	AA(Normal, 55.9%), AG(Medium risk, 37.7%), GG(High risk, 6.4%)	Active methionine synthase is reduced to an active state, maintaining the unblocked methyl transmission pathway

Therefore, before supplementing folic acid, we need to first identify our genotype, and then supplement folic acid individually.

Specification of Folic Acid Utilization Ability Genetic Detection

Applicable Population	Couples trying to conceive, all pregnant women
Sample Types	Whole blood/ Oral cells
TAT	5 working days

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