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Biochip Design & Fabrication

Biochip Design & Fabrication CapitalBiotech

The “I” Microfluidic Array Platform (IMAP), independently developed by CapitalBiotech, is a microfluidic platform for molecular testing based on SNP and InDel biomarkers. It provides an integrated solution encompassing hardware, software, reagents, and consumables, supporting the translation of research findings into deployable testing products.

Applications

  • Birth Defect

  • Disease Susceptibility

  • Personalized Medicine

  • DNA Fingerprinting

  • Variety Identification

  • Genetic Quality Assessment


Biochip Development Process

1
  • Loci confirmation and evaluation

  • Confirmation of product development content and indicators


2
  • Complete gene sequence collection, bioinformatics analysis, primer/probe design, primer/probe synthesis, artificial synthesis of gene fragments

3
  • Complete the screening and optimization of primers and probes, establish and optimize the reagent system, and complete the preliminary finalization of the kit

  • Interpretation software development, testing


4
  • Sample testing, verification, optimization, and acceptance check of kit products

Workflow of IMAP

Microfluidic + KASP

Microfluidic + KASP

Simple: only 1 time sample addition

Flexible: 1 chip can test 1/2/4 samples


Centrifuge and heat-sealing

Centrifuge and heat-sealing: 2 mins

Physical division of each reaction hole

No cross infection in loci


​Amplification

Amplification: 1.5 h

Scan

Scan: 10 mins

Fractal pseudo-color map

Fractal pseudo-color map

Visible QC


One-click output test report

One-click output test report

Biochip Design & Fabrication Application Case

Twenty-three Deafness Gene Mutation Detection Kit [Microfluidic Chip Method]

Developed on the IMAP platform, this kit detects 23 mutations across GJB2, SLC26A4, mitochondrial 12S rRNA, and GJB3 using whole-blood or dried-blood-spot samples. The four genes collectively cover more than 90% of the hereditary deafness-associated variants targeted by the assay.

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Contact with CapitalBiotech

Contact Information
Your Inquiries (Expandable)
Instruments
Detection Kits/Reagents
Research Services
Biochip Design & Fabrication
Diagnostic Services
86-10-69002900
Building C, Block 88 Kechuang 6th Street, Yizhuang Biomedical Park, Beijing