Y Chromosome Microdeletion Gene Detection CapitalBio

Infertility caused by male factors has significantly exceeded that of females, accounting for 60%. The spermatogenesis disorders caused by genetic factors such as chromosomal abnormalities and gene mutations account for more than 30%, of which the Y chromosome microdeletion is the second largest genetic factor leading to male infertility, and the incidence is second only to Klinefelter syndrome (Klinefelter syndrome, 47, XXY), accounting for about 10% of male infertility patients.